The Remarkable Potential of Cannabichromene (CBC) for Nervous System Health

The Remarkable Potential of Cannabichromene (CBC) for Nervous System Health
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The Remarkable Potential of Cannabichromene (CBC) for Nervous System Health

By: Gabriel Ettenson, MS, PT

March 15, 2024

Cannabichromene (CBC) for Nervous System Health

Renowned executive leadership experts James Belasco and Ralph Stayer once highlighted the challenge of change by noting that “people often overvalue the familiar and underestimate the potential benefits of something new.” This insight sheds light on the slow acceptance of “non-intoxicating” cannabinoids in Western society. Despite growing research on these compounds and their interaction with the body’s endocannabinoid system (ECS), many still rely on traditional pharmaceuticals or hope for miracle cures from synthetic, over-the-counter multi-vitamins.

While CBD and CBG have received considerable attention, another cannabinoid, Cannabichromene (CBC), warrants recognition. Often overshadowed by its counterparts, CBC shows promise in several studies. For example, a study published in the Journal of Neurochemistry International in 2013 explored the effects of CBC on adult neural stem progenitor cells (NSPCs). These cells are crucial for brain plasticity and repair. The study found that CBC positively influenced the maturation phase of NSPCs, supporting their viability and differentiation. This has a lot to do with the way our bodies create new neurons and glial cells.

Additionally, a study published in the journal, Life, identified seven mechanisms through which CBC protects and regenerates the nervous system. Researchers labeled CBC a “neurogenesis enhancer” due to its ability to sustain stem cell viability and differentiation. Another significant study from 2023, conducted by Italian scientists, further elucidated CBC’s potential. Using specialized animal spinal cord cells, the researchers discovered CBC’s role in facilitating proper dopamine neuron and glutamate receptor maturation. This finding suggests CBC’s therapeutic potential in protecting and regenerating damaged neurons.

So, how does CBC work? Cannabichromene (CBC) interacts primarily with the endocannabinoid system (ECS), targeting CB1 and CB2 receptors. It may also affect other receptor systems, like transient receptor potential (TRP) channels, including TRPA1 and TRPV1, which are associated with pain and inflammation. CBC’s activation or modulation of these channels may result in pain relief and anti-inflammatory effects. Moreover, CBC could influence the production and activity of endocannabinoids, such as anandamide and 2-AG, by inhibiting enzymes responsible for their breakdown. These are cannabinoids produced within your own body. CBC’s action may elevate endocannabinoid levels, impacting mood, pain, and immune function.

In conclusion, the journey toward accepting the therapeutic potential of “non-intoxicating” cannabinoids like CBC may be slow, but the evidence of their efficacy continues to mount. As highlighted by studies exploring CBC’s impact on neural stem progenitor cells and its role in protecting and regenerating the nervous system, this cannabinoid offers promising avenues for maintaining brain health and function.

CBC’s interaction with the ECS, along with its modulation of various receptor systems and pathways in the body, underscores its multifaceted role in promoting overall well-being. By positively influencing the maturation of neural cells, facilitating proper neurotransmitter receptor development, and regulating inflammation and pain, CBC plays a crucial part in preserving communication within the nervous system.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

About Zilis

Zilis is the creator of UltraCell™, a CBD oil product derived from hemp. Based in Argyle, Texas, a suburb of Dallas-Fort Worth, Zilis is privately held. Visit for more information.



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